Myocarditis, pericarditis and other pericardial diseases.

نویسنده

  • C M Oakley
چکیده

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60 - Pericarditis, Pericardial Tamponade, and Myocarditis

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Background—Constrictive pericarditis represents a serious hemodynamic syndrome that may lead to heart failure. Studies of its pathophysiological mechanisms have been impeded by the lack of an animal model. Methods and Results—Cardiac myosin–induced experimental autoimmune myocarditis in interferon (IFN)– knockout (KO) mice results in increased cardiac inflammation and development of severe gros...

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Novel model of constrictive pericarditis associated with autoimmune heart disease in interferon-gamma-knockout mice.

BACKGROUND Constrictive pericarditis represents a serious hemodynamic syndrome that may lead to heart failure. Studies of its pathophysiological mechanisms have been impeded by the lack of an animal model. METHODS AND RESULTS Cardiac myosin-induced experimental autoimmune myocarditis in interferon (IFN)-gamma-knockout (KO) mice results in increased cardiac inflammation and development of seve...

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عنوان ژورنال:
  • Heart

دوره 84 4  شماره 

صفحات  -

تاریخ انتشار 2000